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Mesothelioma and Asbestos
Asbestos is a natural mineral that comes in thin, long fibres. Workers who are exposed to asbestos regularly risk developing mesothelioma and other lung diseases.
It could take a long time before symptoms begin to manifest after exposure to asbestos. Different asbestos types may cause different symptoms.
Pleural Mesothelioma
Pleural mesothelioma can be found in the lung's outer lining, or pleura. It is the most common mesothelioma form and is responsible for 70 to 79% of all diagnosed cases. This condition causes chest discomfort, shortness of breath and a feeling heaviness.
This type of cancer often caused by exposure to asbestos, which is a grouping of minerals comprised of microscopic fibres. When inhaled, these fibers are absorbed into the lung and cause irritation that causes scarring and DNA mutations. The pleura surrounds the chest cavity and lungs This means that these irritations can affect both the lungs as well as a person's heart. Mesothelioma usually doesn't show symptoms until 30 to 50 year after exposure.
Chest pain and shortness breath are the most frequently reported symptoms. Patients may also experience chest tightness, coughing or difficulty breathing. People with this cancer have a history that includes asbestos exposure at work. Construction, manufacturing and shipbuilding are among the most frequent jobs that put people at high risk of developing pleural mesothelioma. Individuals who have been in the military could be at an especially high risk due to the frequent asbestos usage in Navy vessels and army bunkers.
The TNM (tumors, lymph nodes, and metastases staging system) is the most popular staging system for the pleural cancer. The stage that a patient is at when they are diagnosed will assist their doctor in determining the best treatment plan for them. Patients suffering from pleural mesothelioma who is in stage three or stage four will have a worse outlook than those who are in a less advanced stage. Stage four mesothelioma may spread to the heart, liver or diaphragm. This can make the cancer more difficult to treat, and increase the risk of complications for the patient.
Peritoneal Mesothelioma
As opposed to pleural mesothelioma that is a lung-lining cancer, peritoneal mesothelioma develops in the peritoneum, an elongated membrane that covers the abdominal cavity as well as organs like the intestines and the liver. Similar to pleural mesothelioma mesothelioma is triggered by asbestos exposure. There are only 300-500 cases diagnosed each year this is less than the pleural asbestosis.
Like pleural mesothelioma, the symptoms can take years to show. Patients usually have abdominal pain, and could also experience a mass in their abdomen. The symptoms of this kind of mesothelioma can also include nausea or weight loss, as well as fever. A lot of these symptoms are similar to those experienced by digestive problems, which can lead to incorrect diagnosis.

Typically, doctors can identify mesothelioma through an extensive medical history and physical exam. They may also employ imaging tests like X-rays, CT scans and PET/CT scans to detect mesothelioma. These tests can show cancerous tumors or other indications of cancer that aren't apparent on an X-ray.
These test results allow doctors to diagnose mesothelioma and determine the stage and suggest treatment options. Staging is determined based on the type of cell and whether or whether the cancer has spread to other parts of the body.
The most important mesothelioma-related risk factor is exposure to asbestos. People who have been exposed to asbestos in occupations, like plumbing or electrical work, or in manufacturing and construction are more likely to contract the disease. However, even if individuals aren't employed in these fields, they can still be exposed to asbestos through family members or through other sources. For this reason, anyone who suspects they may be at risk should speak to a doctor. A mesothelioma specialist can assist those who have a history with asbestos to learn more about their risk.
Risk Factors
Asbestos is the primary risk factor in mesothelioma. It accounts for as much as 80% of all cases. Exposure to asbestos can occur through military service, work or living with someone who used to work with asbestos. When exposed to asbestos, small particles are able to be inhaled into abdomen and lungs. These particles can cause irritation to the linings and cause cancerous cells to develop in the mesothelium. Mesothelioma may take between 15 and 60 years to develop following exposure to asbestos.
Santa Clarita asbestos attorney include smoking, genetics and aging. People in their 40s and 50s are at greater chance of developing mesothelioma to people who are younger or more. This is because mesothelioma typically occurs between 20 and 60 years after the initial exposure before the first signs of cancer appear. It is important to remember that mesothelioma may develop in people who have been exposed to asbestos, but did not engage directly with it. This is referred to as indirect or secondary asbestos exposure and can be as hazardous as direct asbestos exposure.
Smoking increases the chance of mesothelioma developing, because it damages the mesothelium. It also makes it more prone to. Furthermore, mesothelioma is worsened by certain diseases like pneumonia and asbestosis. Men are more likely to develop mesothelioma than women. This is due to men being more likely to work with asbestos and experience a more exposure than women. Men are also more likely to have lived with someone who has worked with asbestos, and to have asbestos-containing fibers on their clothing. Women are less likely to come into contact with asbestos and don't typically carry asbestos home on their clothing.
Diagnosis
Mesothelioma is difficult to identify because the symptoms often resemble other diseases. This can lead to victims being wrongly diagnosed.
The first step in diagnosing mesothelioma is for NYU Langone doctors to perform an examination of the body and take down a patient's medical history, including asbestos exposure. Doctors may also order an X-ray of the chest or CT scan to check for lumps and other abnormalities, and also to look for evidence of asbestos exposure in the past like pleural plaques (thickened pleura with calcium deposits) and the accumulation of fluid between the lung and chest wall (known as the pleural effusion).
Other diagnostic tests include an echocardiogram, which examines the heart and blood vessels, and a magnetic resonance imaging, or MRI, test that uses magnets and radio waves to create detailed images of the inside of the body. A surgical biopsy is a different method for doctors to identify mesothelioma. During a surgical biopsy, doctors take a small amount of tissue from the pleura or peritoneum for further testing. A pathologist then examines the tissue with an magnifying glass to determine if it is a cancerous cell.
Mesothelioma is classified according to the mesothelial type involved, whether these cells are benign or malignant and the location of the tumor, its type, and the stage of the cancer. Certain mesothelioma types have greater risk of spreading or metastasizing therefore it is essential to establish a clear diagnosis so doctors can treat it before it becomes out-of-control.
Doctors may also conduct tests in the laboratory on a tumor to find particular proteins, genes, or other factors which can help them identify the characteristics of cancer and plan treatment. These results are referred to as staging.
Treatment
A diagnosis of mesothelioma may be frightening. It is important to remember, however, that cancer can be treated, particularly in its initial stages. Many patients with mesothelioma survive for a long time with the disease, without spreading to other areas of their body.
Exposure to asbestos can trigger mesothelioma via a variety of mechanisms. Asbestos particles, which are too small to see or feel with the naked eye, can be airborne and cause irritation to the lung's lining (pleura). As time passes the irritation causes the formation of scar tissue, which eventually lead to tumors.
The Pleura is a covering that covers the abdomen, heart, and lungs. Mesothelium consists of cells that respond when exposed to asbestos. They cause inflammation of the tissue and cause it to scar. Overtime, these changes lead to the development of malignant mesothelioma tumors.
Shortness of breath, chest discomfort, or the accumulation of fluid on the lungs are all symptoms of pleural Msothelioma. In rare cases, the cancer can be spread to the tissues around the heart and reproductive organs.
If imaging scans reveal an underlying mass in the stomach or lungs doctors will recommend biopsies. In the course of the procedure, doctors remove some of the liquid or tumor for laboratory testing. The results can confirm a mesothelioma diagnosis and determine the most effective treatment plan.
There are a variety of mesothelioma treatments, including surgery, chemotherapy and immunotherapy. Most doctors use a combination of these treatments. Participating in clinical trials for new mesothelioma treatment may also be beneficial to patients. To find out more, patients should speak with mesothelioma specialists who have expertise in treating the condition.